What parents should know about 7-OH

7-hydroxymitragynine (7-OH) is a compound found in tiny amounts in the leaves of the kratom plant. Many products now sold in convenience stores, gas stations, vape shops and online contain 7-OH that has been concentrated or made in a lab, at levels far above anything in the leaf. It acts on the same brain receptors as opioids.

They are typically sold as everyday consumer products in those stores and online—not as lawful dietary supplements. FDA has told companies that concentrated 7-OH tablets, gummies, shots and similar products are not lawful dietary supplements or foods; they reach shelves through regulatory gaps. No one had to show they were safe before they went on sale. The federal DEA has proposed placing concentrated 7-OH in Schedule I; see the legislation tracker.

• Small tablets or “tabs,” often in blister packs or tiny bottles
• Liquid “shots” in small bottles, near the register
• Gummies, powders and capsules
• Vape pens and cartridges
• Names or labels with “7-OH,” “7-hydroxy,” “MIT,” “kratom extract,” “enhanced” or “botanical”

None of these signs proves a child is using anything; many have other causes. They are a reason to check in.

• Unusual sleepiness, “nodding off,” or small pupils
• Itching, sweating, nausea or constipation
• Restlessness, irritability, aches, runny nose or trouble sleeping when they go without it, which can be signs of withdrawal
• Changes in mood, grades, friends or sleep
• Unexplained spending, small packages, or the product types listed above

• Pick a calm moment. Lead with care, not punishment.
• Ask what they’ve seen or heard about “7-OH” or kratom at school or online.
• Explain that “sold in a store” does not mean “tested” or “safe,” and that labels on these products often don’t match what’s inside.
• If they are already using, don’t ask them to stop suddenly on their own. Talk to their doctor; stopping can bring withdrawal, and there is good help available.

• Emergency: 911
• Poison Help: 1-800-222-1222, free and confidential, 24 hours
• 988 Suicide & Crisis Lifeline: call or text 988
• SAMHSA National Helpline (treatment referral, free, 24 hours): 1-800-662-4357
• Your child’s doctor or pediatrician

If a product hurt someone, please report it. Reports help officials see the problem.