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The Wiley Rule

Who supports

Who's supportive

58 of 186 lawmakers we track support action on concentrated 7-OH. Each name shows the evidence: Public statement/vote means a bill sponsorship or recorded vote you can check; Told us they support means the lawmaker's office told us directly. Undecided and opposed are shown only from public records. We are nonpartisan.

NC House

NC Senate

Federal agencies

  • U.S. Food and Drug Administration (FDA)

    Announced warning letters to seven firms marketing concentrated 7-OH products (July 15, 2025). Source (opens in a new tab)

  • U.S. Department of Health and Human Services (HHS)

    Recommended Schedule I thresholds for concentrated 7-OH and MGPI (1 mg per gram or per mL). Source (opens in a new tab)

  • U.S. Drug Enforcement Administration (DEA)

    Published a notice of intent to temporarily place 7-OH and MGPI above a threshold in Schedule I (91 FR 65370, Docket DEA-1570). Source (opens in a new tab)

The numbers behind the cause

Studies in our library, by year

288 published sources. Search them.

  • 20174
  • 20188
  • 201912
  • 202022
  • 202123
  • 202210
  • 202321
  • 202420
  • 202551
  • 202679

What kind of evidence

Lab and animal studies show how it works; human reports show what happens to people.

  • case report51
  • review / commentary50
  • human42
  • in vitro34
  • product / analytical33
  • surveillance28
  • other (regulatory)25
  • animal22

States that have acted

21 states have banned, scheduled or limited concentrated 7-OH. See the list.

  • Banned or scheduled13
  • Limits passed8

See them on the stance maps. Is something wrong or out of date? Tell us. As of 2026-10-15.

Add your name

Stand with families asking for honest labels and an end to concentrated 7-OH and spiked vape products.

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